Date of Award

December 2016

Degree Type

Dissertation

Degree Name

Doctor of Philosophy

Department

Engineering

First Advisor

Guangwu Xu

Committee Members

Kevin F. King, Jun Zhang, Brian S. Armstrong, Yi M. Zou

Keywords

Compressed Sensing, Dictionary Restricted Isometry Property, Magnetic Resonance Imaging, Simulation Software, Total Variation Ell-1 Minimization, Translation Invariant Wavelet

Abstract

The goal of this contribution is to achieve higher reduction factors for faster Magnetic Resonance Imaging (MRI) scans with better Image Quality (IQ) by using Compressed Sensing (CS). This can be accomplished by adopting and understanding better sparsifying transforms for CS in MRI. There is a tremendous number of transforms and optional settings potentially available. Additionally, the amount of research in CS is growing, with possible duplication and difficult practical evaluation and comparison. However, no in-depth analysis of the effectiveness of different redundant sparsifying transforms on MRI images with CS has been undertaken until this work. New theoretical sparsity bounds for the dictionary restricted isometry property constants in CS are presented with mathematical proof. In order to verify the sparsifying transforms in this setting, the experiments focus on several redundant transforms contrasting them with orthogonal transforms. The transforms investigated are Wavelet (WT), Cosine (CT), contourlet, curvelet, k-means singular value decomposition, and Gabor. Several variations of these transforms with corresponding filter options are developed and tested in compression and CS simulations. Translation Invariance (TI) in transforms is found to be a key contributing factor in producing good IQ because any particular translation of the signal will not effect the transform representation. Some transforms tested here are TI and many others are made TI by transforming small overlapping image patches. These transforms are tested by comparing different under-sampling patterns and reduction ratios with varying image types including MRI data. Radial, spiral, and various random patterns are implemented and demonstrate that the TIWT is very robust across all under-sampling patterns. Results of the TIWT simulations show improvements in de-noising and artifact suppression over that of individual orthogonal wavelets and total variation ell-1 minimization in CS simulations. Some of these transforms add considerable time to the CS simulations and prohibit extensive testing of large 3D MRI datasets. Therefore, the FastTestCS software simulation framework is developed and customized for testing images, under-samping patterns and sparsifying transforms. This novel software is offered as a practical, robust, universal framework for evaluating and developing simulations in order to quickly test sparsifying transforms for CS MRI.

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