Event Title

Inhibitory Control in Young Children with Neurofibromatosis Type 1

Mentor 1

Bonnie Klein-Tasman

Location

Union Wisconsin Room

Start Date

24-4-2015 10:30 AM

End Date

24-4-2015 11:45 AM

Description

Neurofibromatosis type 1 (NF1) is a neurodevelopmental genetic disorder which affects approximately 1 in 3,000 people. Children with NF1 have an elevated rates of difficulty in executive functioning, and elevated rates of ADHD. This study aims to examine patterns of change and stability in young children with NF on a measure of inhibitory control. We aim to examine the proportion of children who remained stable, improved or showed worse inhibitory control over time and to compare these groups in regards to age, gender and general cognitive ability. 20 3-6 year olds (14 boys, 6 girls) with NF1 completed two assessment visits and were administered the Tower of Patience task of the Laboratory Temperament Assessment Battery to measure inhibitory control and the Differential Ability Scales II to measure general cognitive ability. Kruskal-Wallis tests were used to test for change in the presence of inhibitory control over time. Independent group t-tests were conducted to examine differences in age, gender and IQ. We expect that a higher proportion of children will show good inhibitory control at T2 compared to T1. We do not have specific hypotheses in regards to age, gender and IQ differences. Many more children with NF1 have significant ADHD symptoms than typically developing children. Examining inhibitory control, a frequent difficulty of children with ADHD, may help determine risk factors for the development of ADHD in children with NF1. This study will further the understanding of the development of inhibitory control in children with NF1.

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Apr 24th, 10:30 AM Apr 24th, 11:45 AM

Inhibitory Control in Young Children with Neurofibromatosis Type 1

Union Wisconsin Room

Neurofibromatosis type 1 (NF1) is a neurodevelopmental genetic disorder which affects approximately 1 in 3,000 people. Children with NF1 have an elevated rates of difficulty in executive functioning, and elevated rates of ADHD. This study aims to examine patterns of change and stability in young children with NF on a measure of inhibitory control. We aim to examine the proportion of children who remained stable, improved or showed worse inhibitory control over time and to compare these groups in regards to age, gender and general cognitive ability. 20 3-6 year olds (14 boys, 6 girls) with NF1 completed two assessment visits and were administered the Tower of Patience task of the Laboratory Temperament Assessment Battery to measure inhibitory control and the Differential Ability Scales II to measure general cognitive ability. Kruskal-Wallis tests were used to test for change in the presence of inhibitory control over time. Independent group t-tests were conducted to examine differences in age, gender and IQ. We expect that a higher proportion of children will show good inhibitory control at T2 compared to T1. We do not have specific hypotheses in regards to age, gender and IQ differences. Many more children with NF1 have significant ADHD symptoms than typically developing children. Examining inhibitory control, a frequent difficulty of children with ADHD, may help determine risk factors for the development of ADHD in children with NF1. This study will further the understanding of the development of inhibitory control in children with NF1.