UWM Digital Commons

Gliding Motility, Protein Secretion, and Virulence of Fish Pathogen Flavobacterium Columnare., Nicole C. Thunes
Theses and Dissertations

A Novel Transcription Factor Cder Regulates the Type III Secretion System in a c-di-GMP Dependent Manner in Dickeya Dadantii, Alaleh Ghasemimianaei
Theses and Dissertations

Complex Regulatory Pathways Connect Vfm Quorum-sensing and Cyclic-di-GMP Signaling to Bacterial Virulence in the Phytopathogen Dickeya Dadantii 3937, Biswarup Banerjee
Theses and Dissertations

Molecular Evolution and Biogeography of the New World Eptesicus Bats, Xueling Yi
Theses and Dissertations

The Effects of Hybridization on Skeletal Morphology in Two Closely Related Populations of Rhesus Macaques (Macaca Mulatta): A Geometric Morphometric Approach, Cody Zachery Schumacher
Theses and Dissertations

The Effects of an R103Q Mutation on the Chemical and Physical Properties of the Enzyme Cytochrome C Nitrite Reductase (ccNiR), Shahama Alam
Theses and Dissertations

Development of New Treatments for Asthma and Neuropathic Pain Based on Ɣ-Aminobutyric Acid a Receptor (GABAAR) Ligands, Nicolas Mark Zahn
Theses and Dissertations

Cell and Molecular Biology 5e: What We Know & How We Found Out. An online, interactive electronic textbook (iText), Gerald Bergtrom
Biological Sciences Faculty Books

Protein-Ligand Binding as a Tool to Identify Antiviral Drugs., Rajdeep Virdi
Theses and Dissertations

Study of Binding Induced Mechanical Stabilization of Proteins Using a Single Molecule Approach, Narayan Prasad Dahal
Theses and Dissertations

Selection and Demography Drive Range-Wide Patterns of Mhc Variation in Mule Deer (odocoileus Hemionus), Rachel M. Cook
Theses and Dissertations

Negative Regulation of the Kinase LIN-45 By the E3/E4 Ubiquitin Ligase UFD-2, Augustin Deniaud
Theses and Dissertations

Roles of Secreted Proteins and Iron Utilization Proteins in Virulence of the Fish Pathogen Flavobacterium Columnare, Rachel Conrad
Theses and Dissertations

Part I: Development of Small-Molecule-Based Probes for the Vitamin D Receptor; Part II: Development of a Scalable Manufacturing Process for Orcein Dye, Tania Roseann Mutchie
Theses and Dissertations

Structure & Function of Enzymes in Two Uncharacterized Gene Clusters from Pseudomonas Brassicacearum & Streptomyces Griseofuscus, Lamia Tabassum Badhon
Theses and Dissertations

Investigation of G Protein-coupled Receptor Quaternary Structure Through Fluorescence Micro-Spectroscopy and Theoretical Modeling: Interdependence Between Receptor-receptor and Receptor-Ligand Interactions, Joel David Paprocki
Theses and Dissertations

Modeling the bidirectional glutamine/ ammonium conversion between cancer cells and cancer-associated fibroblasts, Peter Hinow, Gabriella Pinter, Wei Yan, Shizhen Emily Wang
Mathematical Sciences Faculty Articles

Pump-Probe and Mix-and-Inject Experiments at X-Ray Free Electron Lasers, Suraj Pandey
Theses and Dissertations

Dissecting Molecular Mechanism of Heat Stress on Anther Development in Fragaria Vesca, Shikha Malik
Theses and Dissertations

Rapid Diffusion Observed in Microcrystals By X-ray Free Electron Laser Mix-and-inject Serial Crystallography, Tek Narsingh Malla
Theses and Dissertations

Structural and Functional Characterization of L-Enduracididine Biosynthetic Enzymes, Nemanja Vuksanovic
Theses and Dissertations

Macromolecular Structure Determination at X-Ray Free Electron Lasers from Single-Particle Imaging to Time-Resolved X-Ray Crystallography, Ishwor Poudyal
Theses and Dissertations

A Mechanistic Investigation of Cytochrome C Nitrite Reductase Catalyzed Reduction of Nitrite to Ammonia: The Search for Catalytic Intermediates, SHAHID SHAHID
Theses and Dissertations

Quagga Mussel Induced Phosphorus Cycling Changes in Lake Michigan, Rae-Ann MacLellan-Hurd
Theses and Dissertations

Photobiomodulation Modulates Bioenergetics and Oxidative Stress in an in Vitro Model of Diabetic Retinopathy, Alexandria E. Hall
Theses and Dissertations

Zinc Proteomics: Interactions of Zn2+, Cd2+, and Metal-binding Ligands with Zn-Binding Sites in the Proteome, Eric Daniel Lund
Theses and Dissertations

A Tale of Two Adaptors: the Role of Two Adaptor Proteins in Pseudomonas Aeruginosa CHP Chemosensory System Signal Transduction and Implications for Chemosensory Array Formation, Zachary Hying
Theses and Dissertations

Gene Regulatory Mechanisms Driving Temporal Dynamics of Lineage Specific Differentiation in the Cranial Neural Crest, Maria R. Replogle
Theses and Dissertations

Understanding the Role of Protein Kinases Kin1 and Kin2 in the Protein Folding Pathways in the Yeast Saccharomyces Cerevisiae, Chandrima Ghosh
Theses and Dissertations

Targeting the Γ-Aminobutyric Acid a Receptor (gabaar) to Alleviate Inflammation for Asthma and Neuropathic Pain, Amanda Nicole Nieman
Theses and Dissertations

A Seascape Genetics Approach to Studying Genetic Differentiation in the Bull Kelp Nereocystis Luetkeana, Lily G. Gierke
Theses and Dissertations

The Curious Case of NAD-Cleaving Nudix Hydrolases, Atreyei Ray
Theses and Dissertations

Mechanistic Insights into Translational Silencing of HACL mRNA in Yeast S. Cerevisiae, Leena Sathe
Theses and Dissertations

Flavobacterium Gliding Motility: From Protein Secretion to Cell Surface Adhesin Movements, Joseph Johnston
Theses and Dissertations

Lorelei Localization and Ovule Ultrastructure in Arabidopsis Thaliana, Juleen May Dickson
Theses and Dissertations

An Assessment of BSA Protein Hydrogel Biocompatibility in the Vertebrate Intestinal Tract, Ryan Joseph Garde
Theses and Dissertations

Dissection of Floral Organ Development and Sterility in Sorghum Bicolor, Ashley R. Smith
Theses and Dissertations

Development of Indicators for Human Fecal Pollution Using Deep-Sequencing of Microbial Communities, Shuchen Feng
Theses and Dissertations

Part I: An Investigation of Calcitroic Acid and Its Phase II Conjugates. Part II: Toward the Development of a Novel Orally-available Asthma Treatment Targeting Gabaa Receptors in the Lungs, Olivia B. Yu
Theses and Dissertations

Part I: an Investigation of Calcitroic Acid and Its Phase II Conjugates. Part II: Toward the Development of a Novel Orally-available Asthma Treatment Targeting Gabaa Receptors in the Lungs, Olivia B. Yu
Theses and Dissertations

Design and Synthesis of Achiral and Chiral Imidazodiazepine (IMDZ) GABA(A)R Subtype Selective Ligands for the Treatment of CNS Disorders, as well as Asthma, Guanguan Li
Theses and Dissertations

Renalase as an Intracellular Metabolite Repair Enzyme, Matthew Robert Hoag
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River Bank Inducement Influence on a Shallow Groundwater Microbial Community and Its Effects on Aquifer Reactivity, Natalie June Gayner
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Studies in Molecular Recognition: Non-proteogenic Amino Acids for Antibiotic Studies and Chemosensors for Recognition and Reporting of Metal-ions, Sarah Anne Oehm
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Role of the Two Adaptor Proteins in the Chp Chemosensory System of Pseudomonas Aeruginosa, Swati Sharma
Theses and Dissertations

Time-Resolved Structural Enzymology at X-ray Free Electron Lasers, Tyler Norwood
Theses and Dissertations

Interactions of Viral and Cellular Helicases, Megan Josephine Corby
Theses and Dissertations

New Direct Acting Anti-Virals Inhibiting Hepatitis C Virus Helicase and Insights into How ATP Fuels Helicase Action, Mark Yerukhimovich
Theses and Dissertations

The Heart of the Madder: An Important Prehistoric Pigment and Its Botanical and Cultural Roots, Michelle LaBerge
Theses and Dissertations

Structure-Function Relationships in Bacterial Regulatory Proteins and an Enzyme Involved in Antibiotic Biosynthesis, Lanlan Han
Theses and Dissertations

Part – I: Development of a Two-step Regiospecific Synthetic Route for Multigram Scale Synthesis of Β-carboline Analogs for Studies in Primates as Anti-alcohol Agents,part – II: Design and Synthesis of Novel Antimicrobials for the Treatment of Drug Resistant Bacterial Infections Part – Iii: A Novel Synthetic Method for the Synthesis of the Key Quinine Metabolite (3S)-3-Hydroxyquinine, Veera Venkata Naga Phani Babu Tiruveedhula
Theses and Dissertations

New Insights into the Role of Antimicrobials of Xenorhabdus in Interspecies Competition, Kristin Jean Ciezki
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An Inducible Fluorescent Reporter System to Measure Lux Operon Promoter Activity, Nicole Thunes
Theses and Dissertations

Interaction with Nitric Oxide of the Nitrosomonas Europaea Tetraheme Protein Cytochrome C554, and Two of Its Variants, in Increasingly Reducing Environments, Jennifer M. McGarry
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The Role of PILJ and Its Structural Domains in the Localization and Function of the CHP Chemosensory System in Pseudomonas Aeruginosa, Vibhuti Hemantkumar Jansari
Theses and Dissertations

Biomedical Applications of Mid-Infrared Spectroscopic Imaging and Multivariate Data Analysis: Contribution to the Understanding of Diabetes Pathogenesis, Ebrahim Aboualizadeh
Theses and Dissertations

Sex Differences in Differential Fear Conditioning During the Acquisition and Consolidation of Learned Safety, David Sylvan Reis
Theses and Dissertations

Investigation of Membrane Receptors’ Oligomers Using Fluorescence Resonance Energy Transfer and Multiphoton Microscopy in Living Cells, Ashish K. Mishra
Theses and Dissertations

A Novel Link Between the Chemotaxis and Biofilm Dispersion Systems of Pseudomonas Aeruginosa, Jesse Michael Reinhardt
Theses and Dissertations

Towards Autonomous Microcystin Detection: Investigating Methods for Automation, Maureen Anne Schneider
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Microbial Communities and the Diverse Ecology of Fecal Indicators at Lake Michigan Beaches, Danielle Cloutier
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Symmetry and Reconstruction of Particle Structure from Random Angle Diffraction Patterns, Sandi Wibowo
Theses and Dissertations

Molecular and Functional Analysis of the Pixb Gene in Xenorhabdus Nematophila, John Lucas
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Characterization and Use of Folate Receptor Isoforms for Targeting of Epithelial and Myeloid Cells, Sreya Biswas
Theses and Dissertations

Lateral Replacement of the Lux Operon in a Vibrio Isolated from the Intestine of a Coral Reef Fish, Melissa Lee Whyte
Theses and Dissertations

Structural and Functional Characterization of Acetoacetate Decarboxylase-Like Enzymes, Lisa Mueller
Theses and Dissertations

Discovery and Characterization of a New Group of IS10 Insertion Sequences, Rachel Marie Kinzelman
Theses and Dissertations

The Role of Proteome in Cellular Zn2+ Trafficking and in the Ability of the Fluorescent Zinc Sensors to Image Intracellular Zn2+, Mohammad Rezaul Karim
Theses and Dissertations

The Function of Renalase, Brett Allen Beaupre
Theses and Dissertations

Role of Protein Phosphatase Reg2-Glc7 in the Regulation of the Yeast Stress Response Kinase, Snf1, Marcin Maziarz
Theses and Dissertations

Protective Effects of Pigmentation in Pseudomonas Aeruginosa: Insights on Pyomelanin Production and Inhibition By Ntbc, Laura Marie Ketelboeter
Theses and Dissertations

The Selective Survival of Escherichia Coli in Freshwater Beach Sand, Natalie Ann Rumball
Theses and Dissertations

Arylboronates as H2O2 or Photo-Inducible DNA Cross-Linking Agents: Design, Synthesis, Mechanism, and Anticancer Activity, Yibin Wang
Theses and Dissertations

Reaction of Zinc Proteome with Biologically Important Metal Binding Ligands, Kaniz Fatema
Theses and Dissertations

Porphyrin as a Spectroscopic Probe of Net Electric Fields in Heme Proteins, Hannah Elizabeth Wagie
Theses and Dissertations

Time-Resolved, Near Atomic Resolution Structural Studies at the Free Electron Laser, Jason James Tenboer
Theses and Dissertations

Theoretical Investigation of Interactions and Relaxation in Biological Macromolecules, Koki Yokoi
Theses and Dissertations

Transport Mechanisms for Human Fecal Indicator Bacteria in an Urban Stormwater Basin in Southeastern Wisconsin, Chelsea M. Corson
Theses and Dissertations

Mechanistic Study of Heme Protein-Mediated Nitric Oxide Dioxygenation Using Photolytically Produced Nitric Oxide, Karl Joseph Koebke
Theses and Dissertations

Role of Non-Muscle Myosin II and Calcium in Zebrafish Midbrain-Hindbrain Boundary Morphogenesis, Srishti Upasana Sahu
Theses and Dissertations

Molecular Identification of Mycobacterium Tuberculosis in the Milwaukee County Institution Grounds Cemetery, Helen Marie Werner
Theses and Dissertations

Application of Coumarin Derivatives in DNA-associated Study: Mutation Detection, Site-Specific Labeling, Photoinduced Interstrand Cross-Links and Ligation Reactions, Huabing Sun
Theses and Dissertations

Got Chlorophyll? The Investigation of Two Chlorophyll-Deficient Mutants in Soybean, Taylor Atkinson, Sarah Przybylski, Alicia Meis, Isabela Caulkins, Brittany Erickson
UWM Undergraduate Research Symposium

Isolating and Sequencing the Aconitase-4 Gene, Zachary Coleman
UWM Undergraduate Research Symposium

EVALUATING A DRUG TO BLOCK CELL DEATH IN HUMAN PBMCS, Erin Geddes, Connor Doyle, Allison Byrd
UWM Undergraduate Research Symposium

Cellular Zinc Trafficking: the Zinc Proteome and Its Reactions with Cadmium, Mohammad Ali Namdarghanbari
Theses and Dissertations

Oligomerization of the Sterile-2 G-Protein Coupled Receptor in Yeast Cells in the Presence and Absence of Alpha-Factor Pheromone Using Fluorescence Spectroscopy and Forster Resonance Energy Transfer Analysis, Joel David Paprocki
Theses and Dissertations

Gene Regulatory Pathways Driving Central Nervous System Regeneration in Zebrafish, Ishwariya Venkatesh
Theses and Dissertations

Interaction of Rhizobium Sp. Strain IRBG74 with a Legume (Sesbania Cannabina) and a Cereal (Oryza Sativa), Shubhajit Mitra
Theses and Dissertations

Novel Protein Secretion and Chitin Utilization Machinery of Flavobacterium Johnsoniae, Sampada Suresh Kharade
Theses and Dissertations

Mechanism of the Hydroxylation Reactions Catalyzed By 4-Hydroxyphenylpyruvate Dioxygenase and Hydroxymandelate Synthase, Dhara D. Shah
Theses and Dissertations

Development of Peripheral Innervation in the Frog Xenopus Laevis, Mitali A. Gandhi
Theses and Dissertations

Small RNA, Cyclic-di-GMP and Phenolic Compounds Regulate the Type III Secretion System in Bacterial Phytopathogens, Devanshi Khokhani
Theses and Dissertations

Enzyme Activity, Maturation and Regulation of Anaerobic Reductases in Shewanella Oneidensis MR-1, Kenneth L. Brockman
Theses and Dissertations

The Role of Antimicrobial Compounds in the Life Cycle of the Symbiotic Bacterium, Xenorhabdus Nematophila, Swati Singh
Theses and Dissertations

The Role of GAP-43 Phosphorylation in Axon Behavior in the Developing Zebrafish Visual System, Jennifer Forecki
Theses and Dissertations

Protein Association in Living Cells Using Fret Spectrometry: Application to G-Protein Coupled Receptors, Suparna Patowary
Theses and Dissertations

Evaluating the Influence of Environmental Factors on the Rate of Extra-Pair Matings in Tropical and Temperate Populations of the House Wren (Troglodytes Aedon), Kaitlin Claire McKenney
Theses and Dissertations

A Synthetic Biology Approach to Engineering New Anticancer Agents, Shane Robert Wesener
Theses and Dissertations

Structure and Function of Proteins Investigated By Crystallographic and Spectroscopic Time-Resolved Methods, Namrta Purwar
Theses and Dissertations

Evaluation of Vdr-coactivator Inhibitors Using Biochemical and Cell-based Assays, Athena Marie Baranowski
Theses and Dissertations

Transcending Microbial Source Tracking Techniques Across Geographic Borders: An Examination of Human and Animal Microbiomes and the Integration of Molecular Approaches in Pathogen Surveillance in Brazil and the United States, Amber Mae Koskey
Theses and Dissertations

Zinc Chemical Biology: The Pursuit of the Intracellular Targets of Zinquin, Andrew Nowakowski
Theses and Dissertations

Cellular Metabolism and Its Effect on the Type III Secretion System of Dickeya Dadantii 3937, William Cortrell Hutchins
Theses and Dissertations

Prolonged Glucose Deprivation Sensitizes Snf1 to Negative Regulation By PKA to Delay Entry into Quiescence, Leah Bernadette Doughty
Theses and Dissertations

Towards the Use of Time-Resolved X-ray Crystallography in Mechanistic Studies of Cytochrome c Nitrite Reductase from Shewanella Oneidensis, Matthew David Youngblut
Theses and Dissertations

Methods in Metallomics, Proteomics, and Toxicology: Development and Applications of Laser Ablation Inductively Coupled Plasma Mass Spectrometry and Native SDS-PAGE, William John Wobig
Theses and Dissertations

Quorum Sensing in Vibrios and Cross-Species Activation of Bioluminescence Lux Genes by Vibrio Harveyi LuxR in an Arabinose-Inducible Escherichia Coli Expression System, Anne Marie Wannamaker
Theses and Dissertations

Cell Surface Adhesins, Exopolysaccharides and the Por (Type Ix) Secretion System of Flavobacterium Johnsoniae, Abhishek Shrivastava
Theses and Dissertations

High-Throughput Approaches for the Assessment of Factors Influencing Bioavailability of Small Molecules in Pre-Clinical Drug Development, Megan Marie McCallum
Theses and Dissertations

Gene Expression Response in Early Developmental Stages of Rainbow Trout Exposed to Ecologically Relevant Concentrations of Malathion, Susan Miller
Theses and Dissertations

Part 1. Design and Synthesis of Cysteine/Cystine Prodrugs and Bioisosteres Including Symmetrical and Unsymmetrical Disulfides Designed to Increase Cystine Levels in the CNS in Order to Drive the Cystine/Glutamate Antiporter: A Novel Treatment for Schizophrenia and Drug Addiction. Part 2. Design and Synthesis of Subtype Selective Ester Bioisosteres of BZR Ligands for Gabaa/Benzodiazepine Receptors to Enhance Metabolic Stability, Edward Merle Johnson II
Theses and Dissertations

Investigation of the Quaternary Structure of an ABC Transporter in Living Cells Using Spectrally Resolved Resonance Energy Transfer, Deo R. Singh
Theses and Dissertations

Assessment of Dim Mutants of the Vibrio harveyi species isolated from the Gulf of Mexico, Elizabeth Bolton
Theses and Dissertations

Part I, Unified Pharmacophore Protein Models of the Benzodiazepine Receptor Subtypes ; Part II, Subtype, Terrill S. Clayton
Theses and Dissertations