UWM Digital Commons

Part I Enantiospecific Total Synthesis of Unnatural Enantiomers of C-19 Methylated Sarpagine/Macroline/Ajmaline-Type Biologically Active Indole Alkaloids via the Pictet-Spengler Reaction/Dieckmann Cyclization Process. Part II Design, Synthesis, and Characterization of Novel Gamma-Aminobutyric Acid Type A (GABAA) Receptor Ligands for the Treatment of Neurological Disorders Including Epilepsy, Depr, Kamal Prasad Pandey
Theses and Dissertations

Photo-Reactivity of Bifunctional Naphthalene Compounds Toward DNA, Qi Zhang
Theses and Dissertations

Inducible DNA Interstrand Cross-linking Agents: Design, Synthesis, Mechanism, and Biomedical Applications, Muhammad Asad Uz Zaman
Theses and Dissertations

Enhancement of Energy Efficiency for Thermal Energy and Biomass Driven Applications, OSAMA Mansour Selim ELSAYED
Theses and Dissertations

Part I: Synthesis of Quinolones for Inhibition of the Β-barrel Assembly Machine in Gram Negative Bacteria; Part II: Synthesis of Azo Dye Sensors for Detection of Metal Ions in Aqueous Environments, Katryna Williams
Theses and Dissertations

Investigation into the Measurement of Student Ability: Refinements, Improvements and Enhanced Understanding of Factors That Influence Performance, David Schreurs
Theses and Dissertations

Design and Synthesis of Chiral and Achiral Benzodiazepines and Imidazodiazepines as Α–subtype Selective Gabaar Positive Modulators to Treat Schistosomiasis, Epilepsy, Asthma and Some Mental Disorders, Md Yeunus Mian
Theses and Dissertations

Guest Host Chemistry Part I: The Synthesis of Metal Selective Sensors Part II: The Synthesis of Antibiotic Precursors and Intermediates, Trevor Moss Hagemann
Theses and Dissertations

The Effects of an R103Q Mutation on the Chemical and Physical Properties of the Enzyme Cytochrome C Nitrite Reductase (ccNiR), Shahama Alam
Theses and Dissertations

Study of the Chemical Fabrication Process of NSOM Probes and the Modification of the Probe Surface, Muhammad Nazmul Hussain
Theses and Dissertations

In Vitro and In Vivo Identification and Quantification of Carmofur and 5-Fluorouracil Using Tandem Mass Spectrometry, Mohammad Mohiminul Islam
Theses and Dissertations

The Activity of QH II 66 and It’s Analogs in Medulloblastoma, Melanoma and Non-small Cell Lung Cancer Cell Lines., Taukir Ahmed
Theses and Dissertations

Physicochemical Properties, Pharmacokinetics and Biodistribution of ARM14988, an Acid Ceramidase Inhibitor, and Its Potential as Chemotherapeutic Agent for Glioblastoma, Vilashini Rajaratnam
Theses and Dissertations

Part I: Development of a Novel, Small-Molecule Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice Part II: Synthesis and SAR Studies of Novel HDAC Inhibitors on Prostate Cancer Cell Line: Mechanistic Insights Towards Anticancer Activity, Jawad Bin Belayet
Theses and Dissertations

Solid Sorbents for Improved Chemical Separations: Applications in Nuclear Medicine and Environmental Remediation, Kevin Wolters
Theses and Dissertations

Part I: A Concise Synthesis of Microtubule Inhibitor Tryprostatin A and B and Its Analogs Part II: Brønsted Acid Catalyzed Reactions of Aromatic Ketones with Ethyl Diazoacetate and Its Synthetic Scope, Khorshada Jahan
Theses and Dissertations

Evaluating the Biological Activities of Novel Histone Deacetylase Inhibitors (hdaci) in Adherent and Nonadherent Tumor Cell Lines, Samer Alanani
Theses and Dissertations

Functional Material Systems for Stimuli-Responsive Interference Coloration, Milad Momtaz
Theses and Dissertations

Mass Spectrometry Directed Pre-Clinical Studies of Asthma Candidate MIDD0301 and Its Analogs, Md Shadiqur Rashid Roni
Theses and Dissertations

Design and Synthesis of Achiral and Chiral Benzodiazepines and Imidazodiazepines to Modulate the Activity of Gabaa Receptors for the Treatment of Cancer, CNS Disorders and Pain, Farjana Rashid
Theses and Dissertations

Investigating Provenance and Authenticity Using ICP-MS in the University of Wisconsin-milwaukee Art Collection: a Case Study of Luristan Bronzes, Hannah Rillie
Theses and Dissertations

Part I: Development of Small-Molecule-Based Probes for the Vitamin D Receptor; Part II: Development of a Scalable Manufacturing Process for Orcein Dye, Tania Roseann Mutchie
Theses and Dissertations

Structure & Function of Enzymes in Two Uncharacterized Gene Clusters from Pseudomonas Brassicacearum & Streptomyces Griseofuscus, Lamia Tabassum Badhon
Theses and Dissertations

Determination of the Metabolism, Distribution, and Concentration of Calcitroic Acid, Elliot Di Milo
Theses and Dissertations

Chapter 1: Part A: A Unique Approach of Preparing 3,3-Disubstituted Oxindoles from Acyclic Tetrasubstituted Aldehydes: Total Synthesis of (-)-Coerulescine and (-)-Coixspirolactam A, Chapter 1: Part B: Synthetic Scope of Brønsted Acid Catalyzed Reactions of Carbonyl Compounds and Ethyl Diazoacetate,, Md Shahnawaz Ali
Theses and Dissertations

Approach Toward the Total Synthesis of Some Sarpagine Related Indole Alkaloids: Histrixnine, Gelsempervine A, Gelsempervine B, O-Methylmacusine B & 19,20-Dihydro-O-Methylmacusine B,Design, Synthesis & Biological Study of Some Novel Gamma-Aminobutyric Acid Type (GABAA) Receptor Ligands, Md Zubair Ahmed Khan
Theses and Dissertations

Novel Approaches to the Determination of Toxic Metals in Industrial Waste and Soil Extracts, Garrett Bruce Finn
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A Mechanistic Investigation of Cytochrome C Nitrite Reductase Catalyzed Reduction of Nitrite to Ammonia: The Search for Catalytic Intermediates, SHAHID SHAHID
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Effect of Force and Confinement on Chemical Reaction Kinetics, Alejandro Boscoboinik
Theses and Dissertations

Understanding Mechanochemical Processes on Surfaces Measured in Ultrahigh Vacuum, Resham Rana
Theses and Dissertations

Development of a Novel Sequential Injection-Proton NMR Method for Determining Cathinones in Forensic Samples, Malati Thapa
Theses and Dissertations

Speciation, Transport, and Fate of Heavy Metals in Soils from a Civil War Battlefield: Development of a Novel MAE-GF-AAS Method, Shawn Christopher Salske
Theses and Dissertations

Computational Materials Science and Engineering: Model Development and Case Study, Yihan Xu
Theses and Dissertations

Development of an Advanced Zinc Air Flow Battery System (Phase 2), Jingyu Si
Theses and Dissertations

I. Design and Synthesis of Α6-GABAAR Subtype-selective Pyrazoloquinolinones with Improved Metabolic Stability and Enhanced Bioavailability. II & III. Process Development of Subtype-Selective Α2/3-GABAAR Imidazodiazepines: HZ-166 and KRM-II-81 and Α5-GABAAR Imidazodiazepines: MIDD0301 and GL-II-73, Daniel E. Knutson
Theses and Dissertations

Intracellular Zinc Trafficking: An Interplay of Proteome, Metallothioneine and Glutathione, Afsana Mahim
Theses and Dissertations

Zinc Proteomics: Interactions of Zn2+, Cd2+, and Metal-binding Ligands with Zn-Binding Sites in the Proteome, Eric Daniel Lund
Theses and Dissertations

Characterization of DNA Interstrand Cross-Linking Agents by Liquid Chromatograhy-Mass Spectrometry, Anahit Marina Campbell
Theses and Dissertations

Fundamental Studies of Trivalent F-Element Separations Using Ionic Liquids and Extraction Chromatography: Toward an Improved Talspeak Process, Charles Smith
Theses and Dissertations

Controlling and Manipulating Microscopic Particles in Solution By Using Various Electric Field Geometries, Xavier Sacro Udad
Theses and Dissertations

Chemical Self-Assembly Strategies Toward the Design of Molecular Electronic Circuits, Dustin Olson
Theses and Dissertations

The Curious Case of NAD-Cleaving Nudix Hydrolases, Atreyei Ray
Theses and Dissertations

Probing the Early Steps in the Catalytic Reduction of Nitrite to Ammonia, Catalyzed By Cytochrome C Nitrite Reductase, Md Mahbbat Ali
Theses and Dissertations

Part I: A Concise Asymmetric Synthesis of Microtubule Inhibitor Tryprostatin B Part II: Synthesis and Biological Assessment of Histone Deacetylase (HDAC) Inhibitors Part III: Acid Catalyzed Reactions of Aromatic Ketones with Ethyl Diazoacetate, Md Mizzanoor Rahaman
Theses and Dissertations

Optimizing Hydrogen Sulfide Removal and Biogas Production Using the Water Wash Method, Brian Leightner
Theses and Dissertations

A Study in Molecular Recognition: Synthesis of a Β-sheet Mimic & Quantitation of Metal Ions in Aqueous Solutions Through Solid Supported Semi-selective Chemosensors, Tyler G. Fenske
Theses and Dissertations

Part I: An Investigation of Calcitroic Acid and Its Phase II Conjugates. Part II: Toward the Development of a Novel Orally-available Asthma Treatment Targeting Gabaa Receptors in the Lungs, Olivia B. Yu
Theses and Dissertations

Active Polymeric Materials for 3D Shaping and Sensing, Adebola Oyefusi
Theses and Dissertations

Part I: Design and Synthesis of Novel Drugs to Treat Asthma By Targeting GABAA Receptors in the Lung Part II: Design and Synthesis of Novel Α2/α3 Subtype Selective GABAAR Ligands for CNS Disorders, Rajwana Jahan
Theses and Dissertations

Part I: an Investigation of Calcitroic Acid and Its Phase II Conjugates. Part II: Toward the Development of a Novel Orally-available Asthma Treatment Targeting Gabaa Receptors in the Lungs, Olivia B. Yu
Theses and Dissertations

In Situ Chemical Probing of Vacancy Defects in Graphene and Boron Nitride at Room Temperature, Ali Ihsan Altan
Theses and Dissertations

Design and Synthesis of Achiral and Chiral Imidazodiazepine (IMDZ) GABA(A)R Subtype Selective Ligands for the Treatment of CNS Disorders, as well as Asthma, Guanguan Li
Theses and Dissertations

From General Chemistry to Anatomy and Physiology: Revalidating and Adapting Assessments and Models, Victoria Fisher
Theses and Dissertations

In Situ Chemical Probing of Vacancy Defects in Graphene and Boron Nitride at Room Temperature, Ali Ihsan Altan
Theses and Dissertations

A Real-Time Approach to Process Monitoring of Heavy Metals: Spectrophotometric Characterization and Application of Novel Azo, Joseph Timothy Labeots
Theses and Dissertations

Shorter and Improved Access to the Key Tetracyclic Core of Sarpagine-Macroline-Ajmaline Indole Alkaloids: the Total Synthesis of Alkaloids Macrocarpines A-g, Talcarpine, N(4)-methyl-n(4),21-secotalpinine, Deoxyperaksine, Dihydroperaksine, Talpinine, O-acetyltalpinine, and N(4)-methyltalpinine, Md Toufiqur Rahman
Theses and Dissertations

Graphene-Based Materials Coated on Zeolite for the Removal of Persistent Organic Pollutants from Water, Yan Zhang
Theses and Dissertations

Studies in Molecular Recognition: Non-proteogenic Amino Acids for Antibiotic Studies and Chemosensors for Recognition and Reporting of Metal-ions, Sarah Anne Oehm
Theses and Dissertations

New Approaches to Multi-functional Soft Materials, Seyedali Banisadr
Theses and Dissertations

Integration of Scale-themed Instruction Across the General Chemistry Curriculum and Selected In-depth Studies, Jaclyn Trate
Theses and Dissertations

Development of Pre-Clinical Assays Based on Tandem Mass Spectrometry to Investigate Gabaa Receptor Modulators, Margaret Laurel Guthrie
Theses and Dissertations

Short Synthesis and Biological Evaluation of 5-chloro-7-benzoyl 2,3-dihydrobenzo[b]furan -3-carboxylic Acid(brl-37959) and Its Analogs., Shamsul Arefin Ahmed
Theses and Dissertations

Investigation of Tribochemical Reactions Using the Model System of Methyl Thiolate on Copper Foil in Ultrahigh Vacuum and Ab-Initio Calculations, Heather Loren Adams
Theses and Dissertations

Infrared actuation-induced simultaneous reconfiguration of surface color and morphology for soft robotics, Seyedali Banisadr, Jian Chen
Chemistry and Biochemistry Faculty Articles

Part – I: Development of a Two-step Regiospecific Synthetic Route for Multigram Scale Synthesis of Β-carboline Analogs for Studies in Primates as Anti-alcohol Agents,part – II: Design and Synthesis of Novel Antimicrobials for the Treatment of Drug Resistant Bacterial Infections Part – Iii: A Novel Synthetic Method for the Synthesis of the Key Quinine Metabolite (3S)-3-Hydroxyquinine, Veera Venkata Naga Phani Babu Tiruveedhula
Theses and Dissertations

Investigation of Catalytic Oxidation and Coupling Reactions on Gold, Palladium, and Gold-palladium Alloys, Theodore Douglas Thuening
Theses and Dissertations

A Theoretical Analysis on the Zintl-klemm Concept and Its Extensions, Sandra Maria Simon
Theses and Dissertations

Interaction with Nitric Oxide of the Nitrosomonas Europaea Tetraheme Protein Cytochrome C554, and Two of Its Variants, in Increasingly Reducing Environments, Jennifer M. McGarry
Theses and Dissertations

Fundamental Studies of Metal Ion Extraction into Ionic Liquids By Macrocyclic Polyethers, James Lee Wankowski
Theses and Dissertations

Persistence in STEM: Development of a Persistence Model Integrating Self-efficacy, Outcome Expectations and Performance in Chemistry Gateway Courses, Shalini Srinivasan
Theses and Dissertations

Towards Autonomous Microcystin Detection: Investigating Methods for Automation, Maureen Anne Schneider
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Experimental Methods in Cryogenic Spectroscopy: Stark Effect Measurements in Substituted Myoglobin, Bradley Michael Moran
Theses and Dissertations

Part 1: Design, Synthesis, and Evaluation of Novel Gram-positive Antibiotics Part 2: Synthesis of Dihydrobenzofurans Via a New Transition Metal Catalyzed Reaction Part 3: Design, Synthesis, and Evaluation of Bz/gabaa Α6 Positive Allosteric Modulators, Christopher Michael Witzigmann
Theses and Dissertations

Corrosion of Aluminum Current Collector in Cost Effective Rechargeable Lithium-Ion Batteries, Shengyi Li
Theses and Dissertations

Development of Cellular High Throughput Assays to Determine the Electrophysiological Profile of GABA(A) Receptor Modulators for Neurology and Immunology, Nina Yina Yuan
Theses and Dissertations

The Synthesis of Fluorescent 3, 6-dihydroxyxanthones: A Route to Substituted Fluoresceins, Surajudeen Omolabake
Theses and Dissertations

Structural and Functional Characterization of Acetoacetate Decarboxylase-Like Enzymes, Lisa Mueller
Theses and Dissertations

The Role of Proteome in Cellular Zn2+ Trafficking and in the Ability of the Fluorescent Zinc Sensors to Image Intracellular Zn2+, Mohammad Rezaul Karim
Theses and Dissertations

The Function of Renalase, Brett Allen Beaupre
Theses and Dissertations

Electrical Measurements and Attenuated Total Reflection Infrared Spectroscopic Study of Aromatic Isocyanides and Thiols on Gold, Rasha Khaled Abuflaha
Theses and Dissertations

Synthesis of Subtype Selective Bz/GABAA Receptor Ligands for the Treatment of Anxiety, Epilepsy and Neuropathic Pain, as Well as Schizophrenia and Asthma, Michael M. Poe
Theses and Dissertations

Molecular Recognition in Water: Design, Synthesis, and Characterization of Rigid Molecular Receptors and Enzymatic Mechanistic Probes, Robert William Hoppe
Theses and Dissertations

Seasonal and Spatial Variations in Chemical Composition and Fluxes of Dissolved Organic Matter and Nutrients in the Lower Milwaukee River, Tarek A. Teber
Theses and Dissertations

Development of an Automated Detection System for Nitrite in Aquatic Environments, Tim Schierenbeck
Theses and Dissertations

Encapsulation of Cationic Fluorescent Dyes and Photosensitizers into the Nanoscopic Domains of Poly(ethylene Glycol)-b-poly(ε-caprolactone) Micelles, Zhe Cao
Theses and Dissertations

Variable Pathlength Cavity Spectroscopy Development of an Automated Prototype, Ryan Schmeling
Theses and Dissertations

Synthesis and Performance Analysis of Polyurethane Foam Nanocomposite for Arsenic Removal from Drinking Water, Faten Bakri Hussein
Theses and Dissertations

Arylboronates as H2O2 or Photo-Inducible DNA Cross-Linking Agents: Design, Synthesis, Mechanism, and Anticancer Activity, Yibin Wang
Theses and Dissertations

Part I. The Development of Non-secosteroidal Vitamin D Receptor Modulators Part II. The Development of a Universal GTP-ase Assay, Kelly Ann Teske
Theses and Dissertations

Porphyrin as a Spectroscopic Probe of Net Electric Fields in Heme Proteins, Hannah Elizabeth Wagie
Theses and Dissertations

Mechanistic Study of Heme Protein-Mediated Nitric Oxide Dioxygenation Using Photolytically Produced Nitric Oxide, Karl Joseph Koebke
Theses and Dissertations

Enantiospecific Stereospecific Strategy for the Total Synthesis of Sarpagine and Macroline Related Oxindole Alkaloids: First Total Synthesis of Affinisine Oxindole, Isoalstonisine, Alstofoline, Macrogentine, N(1)-demethylalstonisine, Alstonoxine A and Second Generation Synthesis of Alstonisine, German Oscar Fonseca Cabrera
Theses and Dissertations

Asymmetric Synthesis of All-Carbon α-aryl Quaternary Carbonyl Compounds By Palladium-catalyzed Asymmetric Allylic Alkylation (Pd-AAA) and Their Application to the Synthesis of Biologically Important 3,3′-disubstituted Oxindole and α-disubstituted Quaternary β-lactone Frameworks, Md. Sharif Al Asad
Theses and Dissertations

I. Palladium (0)-Catalyzed Asymmetric Rearrangement of Allyl Enol Ether for the Synthesis of Α -aryl Quaternary Carbon Center. II. Synthesis of Chiral Tryptophan Analogs and Studies Towards Synthesis of Tryprostatin A and B, Md Nazim Uddin
Theses and Dissertations

Improved Extraction Chromatographic Materials for the Separation and Preconcentration of Metal Ions, Abdul Momen
Theses and Dissertations

Chiral Modification of the Pd(111) Surface By Small Organic Molecules, Mausumi Mahapatra
Theses and Dissertations

Asymmetric Synthesis of Tryptophan Driviatives and Its Application to Streamlined Synthesis of Tryprosatain A and B, Matthew Huisman
Theses and Dissertations

Application of Coumarin Derivatives in DNA-associated Study: Mutation Detection, Site-Specific Labeling, Photoinduced Interstrand Cross-Links and Ligation Reactions, Huabing Sun
Theses and Dissertations

Novel Microporous Materials for In-Situ Water Filtration, Alice Lecus
UWM Undergraduate Research Symposium

Lithocholic Acid Analogs as Possible Co-activator Inhibitors for the Vitamin D Receptor, Luis Sanchez
UWM Undergraduate Research Symposium

Cellular Zinc Trafficking: the Zinc Proteome and Its Reactions with Cadmium, Mohammad Ali Namdarghanbari
Theses and Dissertations

Design and Implementation of a Near-field Scanning Optical Module for Inverted Microscopes, Taher Ababneh
Theses and Dissertations

Modification of Pyrimidine and Purine Nucleotides By "Click" Chemistry: Design, Synthesis and Properties Study, Mohammad Mojibul Haque
Theses and Dissertations

Part I: Synthesis and Biological Evaluations of Potent Class L Selective Histone Deacetylase Inhibitors Part II: Aqueous Complexes for Efficient Sizebased Separation of Americium from Curium Part III: Designing Strong Chiral Bronsted Acids and Their Application for Oxaxinanones Derivatization and the Aza-henry Reaction, Joseph Steve Ulicki
Theses and Dissertations

Development of Novel Methods for Characterization of Complex Organic Mixtures By Liquid Chromatography and Raman Spectroscopy, Veronica Maria Marco Alvarez
Theses and Dissertations

The Implications of Content Analysis for the Interpretation of Unguentaria in Museum Collections, Jenna L. Mortensen
Theses and Dissertations

The Synthesis of Alpha 5 Subtype Selective GABA(A) /Benzodiazepine Receptors Ligands, Poonam Biawat
Theses and Dissertations

The Development of VDR-coactivator Inhibitors and Their Evaluation Using Biochemical and Cell-based Assays, Belaynesh Feleke
Theses and Dissertations

Microfluidic Device Integration of Electrostatic Corral Trapping Systems, Alaknanda Amin
Theses and Dissertations

Part I: Studies Towards Asymmetric α-halogenation and Mechanistic Studies of the Acrylate System with Organocatalyst and Part Ii: Synthesis of α-aryl Quaternary Carbon Centers, Maria Shevyrev Shteynbuk
Theses and Dissertations

Wetting, Superhydrophobicity, and Icephobicity in Biomimetic Composite Materials, Vahid Hejazi
Theses and Dissertations

Crown Ether Stereoisomerism: Implications in Metal Ion Extraction and Ionic Liquid Design, Alan Pawlak
Theses and Dissertations

The Surface Chemistry of Adatom Mediated Oligomers of Aromatic Diisocyanides and Dithiols on Au(111) and Granular Films, John Kestell
Theses and Dissertations

Extraction of Indicator Dyes into Imidazolium-Based Ionic Liquids, Sarah Oplawski
Theses and Dissertations

Applying Computational Methods to Interpret Experimental Results in Tribology and Enantioselective Catalysis, Michael Garvey
Theses and Dissertations

An Experimental Investigation Characterizing the Tribological Performance of Natural and Synthetic Biolubricants Composed of Carboxylic Acids for Energy Conservation and Sustainability, Carlton Jonathan Reeves
Theses and Dissertations

Evaluation of Vdr-coactivator Inhibitors Using Biochemical and Cell-based Assays, Athena Marie Baranowski
Theses and Dissertations

Zinc Chemical Biology: The Pursuit of the Intracellular Targets of Zinquin, Andrew Nowakowski
Theses and Dissertations

Studies in Analytical Chemistry and Chemical Education. Part 1: Characterization of Complex Organics By Raman Spectroscopy and Gas Chromatography. Part 2: Differential Item Functioning on Multiple-choice General Chemistry Assessments, Lisa Kay Kendhammer
Theses and Dissertations

I. Studies on the Organocatalytic Formation of Quaternary Stereocenters. II. Studies on the Claisen Rearrangement as a Route to Quaternary Stereocenters. III. Asymmetric Synthesis of Aldehydes Bearing Quaternary Carbon Centers via the Decarboxylative Asymmetric Allylic Alkylation, Eduardo Alberch
Theses and Dissertations

Probing Bonding and Dynamics at Heterogeneous Adsorbate/Graphene Interfaces, Eric Charles Mattson
Theses and Dissertations

Functional Organic Nanomaterials, Ryan R. Kohlmeyer
Theses and Dissertations

Characterization of the Distribution, Abundance, and Fate of Metals in Sediment, April Grant
Theses and Dissertations

Towards the Use of Time-Resolved X-ray Crystallography in Mechanistic Studies of Cytochrome c Nitrite Reductase from Shewanella Oneidensis, Matthew David Youngblut
Theses and Dissertations

Methods in Metallomics, Proteomics, and Toxicology: Development and Applications of Laser Ablation Inductively Coupled Plasma Mass Spectrometry and Native SDS-PAGE, William John Wobig
Theses and Dissertations

Infrared Light Induced Bending of Liquid Crystalline Elastomer Composite-Silicone Bilayer Films, Maika Moua
Theses and Dissertations

An Optical-Fiber Based Sensor Array for the Simultaneous Analysis of Zinc and Copper in Aqueous Environments, Steven Kopitzke
Theses and Dissertations

Anion Effects in the Extraction of Metal Ions into Room-Temperature Ionic Liquids (RTILS), Sarah Lynn Garvey
Theses and Dissertations

High-Throughput Approaches for the Assessment of Factors Influencing Bioavailability of Small Molecules in Pre-Clinical Drug Development, Megan Marie McCallum
Theses and Dissertations

Part I. The First Enantiospecific, Stereospecific Total Synthesis of the Indole Alkaloid Ervincidine. Part II. The Synthesis of Alpha 5 Subtype Selective Ligands for Gaba(a) /Benzodiazepine Receptors, Sundari K. Rallapalli
Theses and Dissertations

Mitochondrial Targeting in Photodynamic Therapy. Metabolic and Drug Structure Requirements for Specific Mitochondrial Localization. A Pilot Investigation, Melissa Rhea Pergande
Theses and Dissertations

The Measure and Instruction of Scale in Introductory Chemistry, Karrie Linn Gerlach
Theses and Dissertations

Rapid Knowledge Assessment (RKA): Assessing Students Content Knowledge Through Rapid, in Class Assessment of Expertise, Erin Margaret O'Connell
Theses and Dissertations

Fundamental and Applied Studies of Metal Ion Extraction by Crown Ethers into Imidazolium-Based Room Temperature Ionic Liquids, Cory Hawkins
Theses and Dissertations

Structure and Chemistry of Model Catalysts in Ultrahigh Vacuum, Joshua D. Walker
Theses and Dissertations

Part 1. Design and Synthesis of Cysteine/Cystine Prodrugs and Bioisosteres Including Symmetrical and Unsymmetrical Disulfides Designed to Increase Cystine Levels in the CNS in Order to Drive the Cystine/Glutamate Antiporter: A Novel Treatment for Schizophrenia and Drug Addiction. Part 2. Design and Synthesis of Subtype Selective Ester Bioisosteres of BZR Ligands for Gabaa/Benzodiazepine Receptors to Enhance Metabolic Stability, Edward Merle Johnson II
Theses and Dissertations