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Silver nanoparticle-based catalysts are used extensively to kill bacteria in drinking water treatment. However secondary contamination and their high cost require scientists to seek alternatives with non-toxicity, high activity and low cost. In this article, we develop a new hydrogel-immobilized lysozyme (h-lysozyme) that shows excellent antibacterial performance, including high activity duration of up to 55 days, inhibition efficiency as high as 99.4%, good recycling capability of up to 11 cycles, a wide temperature window and extremely low concentration. The immobilized lysozyme displayed greatly improved bacterial inhibition with both Gram-negative E. coli and Gram-positive B. subtilis, which enables broad antibacterial applications in various water systems. In parallel, the non-toxic structure and high stability of the hlysozyme without additional contamination make it a promising alternative to nanoparticle catalysts fur use in drinking water purification.
Ye, Y., Klimchuk, S., Shang, M., & Niu, J. (2019). Improved antibacterial performance using hydrogel-immobilized lysozyme as a catalyst in water. RSC Advances, 9(35), 20169-20173. doi:10.1039/c9ra02464f