The Association between family history of substance use disorders (SUD) and executive functioning in youth
Mentor 1
Dr. Krista Lisdahl
Location
Union Wisconsin Room
Start Date
24-4-2015 10:30 AM
End Date
24-4-2015 11:45 AM
Description
Background. Previous research has found that adolescents and young adults who have a family history of substance use disorders (SUD) demonstrate abnormal prefrontal cortex activation (Cservenka, Fair, & Nagel, 2014; Spadoni et al., 2013) and poorer executive functioning (Gierski et al., 2012; Dolan, Bechara, & Nathan, 2008). The goal of the current study is to examine executive functioning in adolescents and young adults with and without a family history of SUD. It is hypothesized that individuals with a family history of SUD will demonstrate poorer working memory, set-shifting, and inhibitory control compared to those without a history of SUD, after controlling for recent substance use. Method. Data were collected from 89 teens and emerging adults, including 63 who did not have a family history of a SUD, and 26 who had at least one parent with a family history of SUD. Exclusionary criteria included independent Axis I disorders (besides SUD), prenatal health issues or significant drug exposure, and medical and neurologic disorders. Multiple regressions will examine the impact of family history of SUD on executive functioning (Wisconsin Card Sorting Task, Letter Number Sequencing, and Stroop tasks) after controlling for age, gender, reading ability, and recent cannabis and alcohol use.
The Association between family history of substance use disorders (SUD) and executive functioning in youth
Union Wisconsin Room
Background. Previous research has found that adolescents and young adults who have a family history of substance use disorders (SUD) demonstrate abnormal prefrontal cortex activation (Cservenka, Fair, & Nagel, 2014; Spadoni et al., 2013) and poorer executive functioning (Gierski et al., 2012; Dolan, Bechara, & Nathan, 2008). The goal of the current study is to examine executive functioning in adolescents and young adults with and without a family history of SUD. It is hypothesized that individuals with a family history of SUD will demonstrate poorer working memory, set-shifting, and inhibitory control compared to those without a history of SUD, after controlling for recent substance use. Method. Data were collected from 89 teens and emerging adults, including 63 who did not have a family history of a SUD, and 26 who had at least one parent with a family history of SUD. Exclusionary criteria included independent Axis I disorders (besides SUD), prenatal health issues or significant drug exposure, and medical and neurologic disorders. Multiple regressions will examine the impact of family history of SUD on executive functioning (Wisconsin Card Sorting Task, Letter Number Sequencing, and Stroop tasks) after controlling for age, gender, reading ability, and recent cannabis and alcohol use.
