Fabrication of a Dielectrophoretic Particle Trap
Mentor 1
Woo Jin Chang
Location
Union Wisconsin Room
Start Date
5-4-2019 1:30 PM
End Date
5-4-2019 3:30 PM
Description
There have been many methods discovered in recent years on how to trap and manipulate individual particles. Processes such as atomic force microscopy and filtration are examples of those, but the problem is that they all require mechanical control of the cell, which is undesirable. Dielectrophoresis uses non-uniform electric fields to trap individual cells, instead of using a probe or other method of mechanical control, which limits the damage to the cell. Dielectrophoresis (DEP) is a phenomenon in which a force is exerted on a dielectric particle when it is subjected to a non-uniform electric field. The particle can be neutrally charged, and the force will still be exerted. The goal of this research was to fabricate dielectrophoretic chips that would allow particles to be injected into the chip and be subject to dielectrophoresis. After fabrication, the efficiency of the traps was tested. DEP will play a big role in both cancer and stem cell research due to the advantage of being able to examine a single cell at a time without damaging the cell.
Fabrication of a Dielectrophoretic Particle Trap
Union Wisconsin Room
There have been many methods discovered in recent years on how to trap and manipulate individual particles. Processes such as atomic force microscopy and filtration are examples of those, but the problem is that they all require mechanical control of the cell, which is undesirable. Dielectrophoresis uses non-uniform electric fields to trap individual cells, instead of using a probe or other method of mechanical control, which limits the damage to the cell. Dielectrophoresis (DEP) is a phenomenon in which a force is exerted on a dielectric particle when it is subjected to a non-uniform electric field. The particle can be neutrally charged, and the force will still be exerted. The goal of this research was to fabricate dielectrophoretic chips that would allow particles to be injected into the chip and be subject to dielectrophoresis. After fabrication, the efficiency of the traps was tested. DEP will play a big role in both cancer and stem cell research due to the advantage of being able to examine a single cell at a time without damaging the cell.
